Resident
Cardwell, Sean, PharmD
Residency Program
LMPS
Project Title
Co-Infections, Complications and Clinical Outcomes in COVID-19 Patients during the Second and Third Wave (4C’s)
Investigators
Zahra Kanji, B.Sc (Pharm), PharmD, ACPR, FCSHP, Alex Pai, B.Sc (Biochem), PharmD, ACPR
Abstract
The preceding 3C’s study described the incidence of co-infections and rate of inappropriate antibiotic prescribing in COVID-19 patients at Lions Gate Hospital (LGH) during the first pandemic wave. Since then, corticosteroids and interleukin 6 inhibitors have become the standard of care, however, may be associated with an increased risk of late co-infections. This retrospective cohort study characterizes 132 COVID-19 patients admitted to LGH between July 2020 to June 2021 and describes incidences of co-infection, anti-infective prescribing patterns and patient outcomes. Late co-infections developed in 18.2% of patients and were associated with increased immunosuppressive therapy use, ICU admission & covid-related complications.
